ODCs

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1 OMIM reference -
1 associated gene
16 signs/symptoms

PROTEIN INTERACTIONS: 1
COMMON SIGNS: 4

1 OMIM reference -
1 associated gene
8 signs/symptoms

Atypical teratoid tumor

Hereditary cerebral hemorrhage with amyloidosis, Dutch type


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	SMARCB1	(0.56)	APP

Citations in the biomedical literature:

Atypical teratoid tumor		Hereditary cerebral hemorrhage with amyloidosis, Dutch type
	Synonym(s): (no synonyms)		Synonym(s): - HCHWA, Dutch type - HCHWA-D

	Classification (Orphanet): - Rare neurologic disease - Rare oncologic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease - Rare systemic or rheumatologic disease

	Classification (ICD10): (no data available)		Classification (ICD10): (no data available)

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: adult Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - 2 MeSH references: C537944 / D028243


COMMON SIGNS	- Early death / lethality - Facial pain / cephalalgia / migraine - Intracranial / cerebral calcifications - Seizures / epilepsy / absences / spasms / status epilepticus

Atypical teratoid tumor		Hereditary cerebral hemorrhage with amyloidosis, Dutch type
	Very frequent - Central nervous system / peripheral nerves neoplasm / tumor / carcinoma / cancer - Humour troubles / anxiety / depression / apathy / euphoria / irritability - Nausea / vomiting / regurgitation / merycism / hyperemesis Frequent - Ataxia / incoordination / trouble of the equilibrium - Hemiplegia / diplegia / hemiparesia / limb palsy - Hydrocephaly - Macrocephaly / macrocrania / megalocephaly / megacephaly - Muscle weakness / flaccidity - Restricted joint mobility / joint stiffness / ankylosis - Sleep and vigilance disorders Occasional - Acute palsy - Cranial nerves palsy		Very frequent - Intracranial / cerebral / meningeal hemorrhage - Psychic / behavioural troubles - Psychic / psychomotor regression / dementia / intellectual decline Frequent - Transient cerebral ischemia / stroke